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Preparation and properties of nano SiO2 core-shell structured additives and their nanocomposite with polypropylene

KE Yangchuan, SUN Mingzhuo, SONG Yanxin, YANG GuangFu

《化学科学与工程前沿（英文）》 2007年 第1卷 第1期   页码 76-80 doi: 10.1007/s11705-007-0016-6

摘要： To improve the performance of traditional nucleation additives and their compatibility with other additives, as well as to solve complex problems in practical applications, SiO precursors were reactively grafted in situ with the symmetrical hydroxyl groups of the nucleation agents. With this approach, the dissymmetrical part of the nucleation agents plays an important role. As a result, the prepared composite additive the nanoparticle precursor (NPP0) produces excellent results. The NPP0-PP composite has a transparency of over 93%, haze lower than 15%, and a heat distortion temperature (HDT) of 142?C, which is more than the 110?C of the pure PP matrix. In addition, it maintains over 90% of the mechanical properties with a deformation coefficient less than 1%. This indicates a strong nanoeffect.

关键词： deformation coefficient     distortion temperature     excellent     NPP0-PP     traditional nucleation    

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Effects of seeding nucleation agent on geopolymerization process of fly-ash geopolymer

Lapyote PRASITTISOPIN, Issara SEREEWATTHANAWUT

《结构与土木工程前沿（英文）》 2018年 第12卷 第1期   页码 16-25 doi: 10.1007/s11709-016-0373-7

摘要： Geopolymer, an inorganic aluminosilicate material activated by alkaline medium solution, can perform as an inorganic adhesive. The geopolymer technology has a viability to substitute traditional concrete made of portland cement (PC) because replacing PC with fly ash leads to reduced carbon dioxide emissions from cement productions and reduced materials cost. Although fly ash geopolymer stimulates sustainability, it is slow geopolymerization reaction poses a challenge for construction technology in term of practicality. The development of increasing geopolymerization reaction rate of the geopolymer is needed. ?The purpose of this study is to evaluate seeding nucleation agents (NA) of fly ash geopolymer that can accelerate polymerization reactions such that the geopolymer can be widely used in the construction industry. Results from the present study indicate that the use of NA (i.e., Ca(OH) ) can be potentially used to increase geopolymerization reaction rate and improve performance characteristics of the fly ash geopolymer product.

关键词： fly ash     geopolymer     nucleation agent     portland cement replacement    

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Primary nucleation of lithium carbonate

Yuzhu SUN, Xingfu SONG, Jin WANG, Yan LUO, Jianguo YU

《化学科学与工程前沿（英文）》 2009年 第3卷 第1期   页码 73-77 doi: 10.1007/s11705-009-0091-y

摘要： A set of laser apparatus was used to explore the induction period and the primary nucleation of lithium carbonate. Results show that the induction period increases with the decrease of supersaturation, temperature and stirring speed. Through the classical theory of primary nucleation, many important properties involved in primary nucleation under different conditions were obtained quantitatively, including the interfacial tension between solid and liquid, contact angle, critical nucleus size, critical nuleation free energy etc.

关键词： lithium carbonate     primary nucleation     reactive crystallization     induction period    

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Numerical study and control method of interaction of nucleation and boundary layer separation in condensing

Liansuo AN , Zhi WANG , Zhonghe HAN ,

《能源前沿（英文）》 2009年 第3卷 第3期   页码 254-261 doi: 10.1007/s11708-009-0047-4

摘要： The spontaneous nucleation flow in turbine cascade was numerically studied. The model was implemented within a full Navier–Stokes viscous flow solution procedure and the process of condensation was calculated by the quadrature method of moments that shows good accuracy with very broad size distributions. Results were presented for viscous and inviscous flow, showing the influence of boundary layer separation and wake vortices on spontaneous nucleation. The results show that the degree of flow separation in wet steam flow is greater than that in superheated steam flow due to condensation shock and that the loss cannot be neglected. Furthermore, the impact of boundary layer separation and wake vortices on velocity profiles and its implications for profile loss were considered. The calculations showed that layer separation and wake vortices influence nucleation rate, leading to different droplet distributions. A method for controlling homogeneous nucleation and for reducing degree of flow separation in high-speed transonic wet steam flow was presented. The liquid phase parameter distribution is sensitive to the suction side profile of turbine cascade, which impacts the nucleation rate distribution leading to different droplet distributions and affects the degree of flow separation. The numerical study provides a practical design method for turbine blade to reduce wetness losses.

关键词： wet steam     two-phase flow     spontaneous condensation     numerical simulation     flow separation     profile loss    

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Nucleation and growth mechanism of cefodizime sodium at different solvent compositions

Xinwei ZHANG, Shudong ZHANG, Xiaodan SUN, Zequn YIN, Quanjie LIU, Xiwen ZHANG, Qiuxiang YIN

《化学科学与工程前沿（英文）》 2013年 第7卷 第4期   页码 490-495 doi: 10.1007/s11705-013-1350-5

摘要： The induction time of cefodizime sodium was measured in ethanol-water at different solvent compositions by the laser technology measurement. The results indicate that the solvent composition played an important role in the supersaturation and the nucleation process of cefodizime sodium solution. According to the modified classical nucleation theory, the nucleation and growth mechanism were identified. The correlation results show that heterogeneous nucleation dominated the nucleation process at lower supersaturation, where homogeneous nucleation is the most important mechanism at higher supersaturation. Based on the correlated results, the 2D mediated growth mechanism had the highest correlation coefficients ( ), so this mechanism was selected as the proper growth mechanism for cefodizime sodium.

关键词： cefodizime sodium     induction time     primary nucleation     growth mechanism    

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Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China

Jian Wang, Wen Zou

《医学前沿（英文）》 2011年 第5卷 第2期   页码 123-126 doi: 10.1007/s11684-011-0124-z

摘要： Traditional Chinese medicine (TCM) has become widely used in the treatment of acquired immune deficiency syndrome (AIDS) in China in recent years. In this article, we summarize the recent major developments in human immunodeficiency virus/AIDS (HIV/AIDS) treatment with TCM. The use of TCM is associated with preventing or alleviating HIV-related symptoms, reducing treatment side effects, and improving the quality of life. The potential beneficial effects of TCM should be confirmed through extensive and rigorous trials.

关键词： HIV/AIDS     traditional Chinese medicine    

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Interfacial induction and regulation for microscale crystallization process: a critical review

《化学科学与工程前沿（英文）》 2022年 第16卷 第6期   页码 838-853 doi: 10.1007/s11705-021-2129-8

摘要： Microscale crystallization is at the frontier of chemical engineering, material science, and biochemical research and is affected by many factors. The precise regulation and control of microscale crystal processes is still a major challenge. In the heterogeneous induced nucleation process, the chemical and micro/nanostructural characteristics of the interface play a dominant role. Ideal crystal products can be obtained by modifying the interface characteristics, which has been proven to be a promising strategy. This review illustrates the application of interface properties, including chemical characteristics (hydrophobicity and functional groups) and the morphology of micro/nanostructures (rough structure and cavities, pore shape and pore size, surface porosity, channels), in various microscale crystallization controls and process intensification. Finally, possible future research and development directions are outlined to emphasize the importance of interfacial crystallization control and regulation for crystal engineering.

关键词： interfacial crystallization     heterogeneous nucleation     supersaturation     micro/nanostructure     process control and intensification    

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Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

《医学前沿（英文）》 doi: 10.1007/s11684-023-1040-8

摘要： Traditional Chinese medicine (TCM) has played an important role in the prevention and treatment of coronavirus disease 2019 (COVID-19) epidemic in China. The integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention and treatment. According to a series of evidence-based studies, TCM can reduce the infection rate of severe acute respiratory syndrome coronavirus 2 in high-risk groups. For patients with mild and moderate forms of COVID-19, TCM can relieve the related signs and symptoms, shorten the period of nucleic-acid negative conversion, and reduce conversion rate to the severe form of the disease. For COVID-19 patients with severe and critical illnesses, TCM can improve inflammatory indicators and blood oxygen saturation, shorten the hospital stay, and reduce the mortality rate. During recovery, TCM can improve patients’ symptoms, promote organ function recovery, boost the quality of patients’ life, and reduce the nucleic-acid repositive conversion rate. A series of mechanism research studies revealed that capability of TCM to treat COVID-19 through antiviral and anti-inflammatory effects, immune regulation, and protection of organ function via a multicomponent, multitarget, and multipathway approach.

关键词： traditional Chinese medicine     COVID-19     SARS-CoV-2     clinical evidence-based study     mechanism     integrated traditional Chinese and Western medicine    

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Barriers and countermeasures in developing traditional Chinese medicine in Europe

null

《医学前沿（英文）》 2016年 第10卷 第3期   页码 360-376 doi: 10.1007/s11684-016-0455-x

摘要：

Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were from World Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China’s TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines.

关键词： traditional Chinese medicine     Europe     development    

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Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues

Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu

《医学前沿（英文）》 2011年 第5卷 第2期   页码 203-207 doi: 10.1007/s11684-011-0138-6

摘要： Traditional Chinese medicine (TCM) is one of the rarely existing ancient traditional medicines that hold systematic theories as well as preventative and therapeutic methods for diseases in practice. From the 1950s, such research methods as mathematics, statistics, and data mining (DM) have been gradually introduced to TCM studies, making it more scientific. Meanwhile, the distinct features of TCM theories and diagnostic-model have constantly challenged the methodology of statistics. This paper introduces the following scientific features of traditional Chinese therapeutics: 1) its goal is to balance the functions and conditions of human body; 2) it emphasizes on holism and individualization; 3) it stresses the longitudinal regulation and evaluation mode, which is a circle of syndrome diagnosis, treatment and evaluation; 4) the interventions of TCM are abundant, compound and natural; and 5) humanistic thought is everywhere. Some statistical problems are raised based on these features. First, complex statistical methods that can analyze subjective indexes and latent variables, multidimensional and multistage data, non-equilibrium designed studies, and longitudinal data are required. Second, comprehensive evaluation on multiple-target mechanism has been brought in by combination treatment. Third, there is a need to analyze how humanity and related cultural factors may influence the effect of interventions. Thus, promoting implemented studies of statistics as well as carrying out the TCM scientific propositions have become the common expectations of both TCM and modern medicine.

关键词： traditional Chinese therapeutics     feature     statistic    

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Applications of dynamical complexity theory in traditional Chinese medicine

null

《医学前沿（英文）》 2014年 第8卷 第3期   页码 279-284 doi: 10.1007/s11684-014-0367-6

摘要：

Traditional Chinese medicine (TCM) has been gradually accepted by the world. Despite its widespread use in clinical settings, a major challenge in TCM is to study it scientifically. This difficulty arises from the fact that TCM views human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. As a result, conventional tools that are based on reductionist approach are not adequate. Methods that can quantify the dynamics of complex integrative systems may bring new insights and utilities about the clinical practice and evaluation of efficacy of TCM. The dynamical complexity theory recently proposed and its computational algorithm, Multiscale Entropy (MSE) analysis, are consistent with TCM concepts. This new system level analysis has been successfully applied to many health and disease related topics in medicine. We believe that there could be many promising applications of this dynamical complexity concept in TCM. In this article, we propose some promising applications and research areas that TCM practitioners and researchers can pursue.

关键词： traditional Chinese medicine     Multiscale Entropy     dynamical complexity     system level     applications    

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Understanding channel tropism in traditional Chinese medicine in the context of systems biology

null

《医学前沿（英文）》 2013年 第7卷 第3期   页码 277-279 doi: 10.1007/s11684-013-0273-3

摘要：

Channel tropism is investigated and developed through long-term clinical practice. In recent years, the development of channel tropism theory has attracted increasing attention. This study analyzed channel tropism theory and the problems associated with it. Results showed that this theory and systems biology have a similar holistic viewpoint. Systems biology could provide novel insights and platform in the study of channel tropism. Some problems in channel tropism theory, including pharmacology and action mechanism, were investigated.

关键词： systems biology     channel tropism theory     traditional Chinese medicine     application    

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Applications of traditional pump design theory to artificial heart and CFD simulation

WANG Yingpeng, SONG Xinwei, YING Chuntong

《能源前沿（英文）》 2008年 第2卷 第4期   页码 504-507 doi: 10.1007/s11708-008-0059-5

摘要： A novel heart pump model was obtained by improving the traditional axial pump design theory with the consideration of working and hydraulic situations for artificial hearts. The pump head range and the velocity triangle were introduced and an iterative approach was utilized for the initial model. Moreover, computational fluid dynamics (CFD) simulations were performed to determine relevant model parameters. The results show that this procedure can be used for designing a series of high-efficiency artificial heart pumps.

关键词： computational     high-efficiency artificial     iterative approach     artificial     traditional    

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

null

《医学前沿（英文）》 2014年 第8卷 第3期   页码 358-361 doi: 10.1007/s11684-014-0348-9

摘要：

This study proposes the ontological reconstruction of the current clinical terminology of traditional Chinese medicine (TCM). It also provides an overview of preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinical terminology. We conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation from the idealized organizational model to real-world implementation and to a formalized, shared, and knowledge-based framework.

关键词： ontology     traditional Chinese medicine     clinical terminology    

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Clinical research of traditional Chinese medicine in big data era

null

《医学前沿（英文）》 2014年 第8卷 第3期   页码 321-327 doi: 10.1007/s11684-014-0370-y

摘要：

With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named “The Fourth Paradigm,” has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the “causality inference” to “correlativity analysis.” This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training.

关键词： big data     traditional Chinese medicine     clinical evaluation     evidence based medicine    

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标题 作者 时间 类型 操作

Preparation and properties of nano SiO2 core-shell structured additives and their nanocomposite with polypropylene

KE Yangchuan, SUN Mingzhuo, SONG Yanxin, YANG GuangFu

期刊论文

Effects of seeding nucleation agent on geopolymerization process of fly-ash geopolymer

Lapyote PRASITTISOPIN, Issara SEREEWATTHANAWUT

期刊论文

Primary nucleation of lithium carbonate

Yuzhu SUN, Xingfu SONG, Jin WANG, Yan LUO, Jianguo YU

期刊论文

Numerical study and control method of interaction of nucleation and boundary layer separation in condensing

Liansuo AN , Zhi WANG , Zhonghe HAN ,

期刊论文

Nucleation and growth mechanism of cefodizime sodium at different solvent compositions

Xinwei ZHANG, Shudong ZHANG, Xiaodan SUN, Zequn YIN, Quanjie LIU, Xiwen ZHANG, Qiuxiang YIN

期刊论文

Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China

Jian Wang, Wen Zou

期刊论文

Interfacial induction and regulation for microscale crystallization process: a critical review

期刊论文

Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

期刊论文

Barriers and countermeasures in developing traditional Chinese medicine in Europe

null

期刊论文

Analysis on the distinguishing features of traditional Chinese therapeutics and related statistical issues

Jingqing Hu, Jie Qiao, Deying Kang, Baoyan Liu

期刊论文

Applications of dynamical complexity theory in traditional Chinese medicine

null

期刊论文

Understanding channel tropism in traditional Chinese medicine in the context of systems biology

null

期刊论文

Applications of traditional pump design theory to artificial heart and CFD simulation

WANG Yingpeng, SONG Xinwei, YING Chuntong

期刊论文

Ontological reconstruction of the clinical terminology of traditional Chinese medicine

null

期刊论文

Clinical research of traditional Chinese medicine in big data era

null

期刊论文